New Assessment of Gleason Grading System in Prostatic Adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Gleason grading of prostatic adenocarcinoma with glomeruloid features on needle biopsy.
Glomerulations in prostatic adenocarcinoma are characterized by dilated glands containing intraluminal cribriform structures with a single point of attachment, resembling a renal glomerulus. On prostate biopsy, glomerulations are exclusively associated with carcinoma and not associated with benign mimickers. However, the Gleason grading of carcinoma with glomerulations on needle biopsy remains ...
متن کاملInterobserver reproducibility of Gleason grading of prostatic carcinoma: urologic pathologists.
Gleason grading is now the most widely used grading system for prostatic carcinoma in the United States. However, there are only a few studies of the interobserver reproducibility of this system, and no extensive study of interobserver reproducibility among a large number of experienced urologic pathologists exists. Forty-six needle biopsies containing prostatic carcinoma were assigned Gleason ...
متن کاملFactors predicting prostatic biopsy Gleason sum under grading.
PURPOSE We determined clinical factors affecting the under grading of biopsy Gleason sum compared with prostatectomy pathology and developed a model predicting the probability of under grading. MATERIALS AND METHODS We analyzed a cohort of 1,701 patients treated for prostate cancer at our institution between 1988 and 2007 with complete biopsy and pathological data available. Patients with a b...
متن کاملThe 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System.
In November, 2014, 65 prostate cancer pathology experts, along with 17 clinicians including urologists, radiation oncologists, and medical oncologists from 19 different countries gathered in a consensus conference to update the grading of prostate cancer, last revised in 2005. The major conclusions were: (1) Cribriform glands should be assigned a Gleason pattern 4, regardless of morphology; (2)...
متن کاملCorrelation between staining intensity of prostatic adenocarcinoma with P53 and Gleason's grading
Introduction: Prostatic adenocarcinoma is the most common malignancy of internal system and after lung cancer is the second cause of death in male. Genetic base of many neoplasms is related to suppressor tumor gene such as P53. Therefore, we aimed in this study, to assess the intensity of prostatic adenocarcinoma tissue staining with P53 staining method and its relationship with Gleason grade. ...
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ژورنال
عنوان ژورنال: Journal of Urological Surgery
سال: 2016
ISSN: 2148-9580
DOI: 10.4274/jus.796